Animal to Human Extrapolation

In extrapolating from animal data to potential human toxicity, a number of conversion factors are used to account for the differences between humans and animals. Factors must consider individual differences within a species; account for different sensitivities (Table 11.8.2); and note the variations between the two species, such as differences in weight, surface area, metabolism, and absorption.

Extrapolation from animal species to humans has elements of both science and art. It serves as a best estimate, neither invalid nor absolute truth. Although each step of assessment is laden with controversy, animal testing is the generally accepted approach for predicting human toxic-

ity.

Project Earth Conservation

Project Earth Conservation

Get All The Support And Guidance You Need To Be A Success At Helping Save The Earth. This Book Is One Of The Most Valuable Resources In The World When It Comes To How To Recycle to Create a Better Future for Our Children.

Get My Free Ebook


Post a comment