Synthetic Multiple Interaction Pirkle Stationary Phases

Figure 1 Enantiomer separation on CSPs is made possible by formation of transient diastereomeric adsorbates with differing free energies. In this illustration, the analyte enantiomers are depicted as right and left hands, and the CSP is depicted as immobilized right-handed gloves.

of simultaneous, geometrically constrained, intermolecular interactions utilizing forces such as hydrogen bonding, n-n attraction, ionic interactions, and steric repulsion can result in diastereomeric adsorbates with differing free energies, the prerequisite for enantioseparation.

Brush-type CSPs are just one of the several types of CSPs that have been developed to date. Other types include CSPs based on natural polymers such as polysaccharides or proteins, artificial polymers, and 'imprinted' polymers. Exactly what constitutes a brush-type CSP is a matter of some debate. In the broadest definition, CSPs based on immobilized cyclodextrins, antibiotics, etc. should perhaps be included in this category. However, this article will deal primarily with the synthetic CSPs developed by Professor William H Pirkle.

Solar Panel Basics

Solar Panel Basics

Global warming is a huge problem which will significantly affect every country in the world. Many people all over the world are trying to do whatever they can to help combat the effects of global warming. One of the ways that people can fight global warming is to reduce their dependence on non-renewable energy sources like oil and petroleum based products.

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