Solvents

The solvent, besides acting as the medium in which the polymerization is performed, has an important secondary role as a porogen. It controls the porous structure of the polymer matrix to a large extent, and a good porogen is essential if one wants the porous structure in the polymer to be well developed. Sometimes, however, a good porogenic solvent can be a bad solvent for the analyte, so once again a compromise is sometimes required. Common imprinting solvents include toluene, chloroform and acetonitrile.

In non-covalent imprinting, there is one further solvent effect which is of great importance. Polar solvents destabilize the analyte-functional monomer assembly and it is therefore better to use non-polar solvents, whenever possible, to maximize the concentration of the assembly in the pre-polymerization mixture. The same argument applies for analyte re-binding. In spite of this, non-covalent imprints have in some cases still shown good recognition properties in aqueous buffers, which are of course highly polar.

One final point of note, which applies to both covalent and non-covalent approaches, is that the best recognition is generally observed when the solvent used for both the polymerization and analyte rebinding is the same.

Solar Panel Basics

Solar Panel Basics

Global warming is a huge problem which will significantly affect every country in the world. Many people all over the world are trying to do whatever they can to help combat the effects of global warming. One of the ways that people can fight global warming is to reduce their dependence on non-renewable energy sources like oil and petroleum based products.

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