Principles

Correlation chromatography (CC, multiplex chromatography, multiple input chromatography)

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belongs to the family of multiplex methods and is essentially statistical in nature. It is a typical example of an integrated product of chemometric principles and an analytical technique. A schematic set-up of a CC system is shown in Figure 1.

In conventional chromatography the sample is injected over a short time, and the response of the chromatographic system - the chromatogram - can be considered as an impulse response. In CC the input

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