Prep GC What Scale

Table 2 gives examples of production scales obtained with different column diameters. Of course, these are typical figures and, depending on the particular application, the actual figures may be five times bigger or smaller.

Preparative large scale GC can be used to purify hundreds of grams a week or hundreds of tonnes a year, as shown here.

6 g per injection on a 40 mm i.d. column x 4 injections per hour x 24 hrs per day x 4 days per week = 2.3 kg per week

Table 3 Examples of applications of preparative GC

1.5 kg per injection on a 600 mm i.d. column x 4 injections per hour x 24 hours per day x 300 days per year = 43 tonnes per year

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