In addition to amino acid mixtures, another difficult class of compounds to deal with is the acidic metabolites of physiological fluids. Even when compounds with amino groups are not present (except in the case of glycine conjugates), the various classes of acids present - mono-, di- and tricarboxylic acids, keto and hydroxycarboxylic acids, aromatic acids with substituted chains, etc. - make sample preparation particularly challenging. There are one-step, one-reagent procedures that are able to derivatize most protic groups in such a mixture of analytes. These can be effective with alkylating or silylating reagents and also with chloroformates, under the active participation of a component in the reaction medium.

Solar Panel Basics

Solar Panel Basics

Global warming is a huge problem which will significantly affect every country in the world. Many people all over the world are trying to do whatever they can to help combat the effects of global warming. One of the ways that people can fight global warming is to reduce their dependence on non-renewable energy sources like oil and petroleum based products.

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