Ionization in Tandem Mass Spectrometry

Although all of the currently available methods of ionization are applicable to tandem mass spectro-metry, where planar separations are involved the choice is limited to EI/CI and FAB/LSIMS. Although electron ionization (EI) is still the most commonly encountered method of ionization, and is used extensively in MS-MS studies, ionization methods such as FAB/LSIMS and CI, which normally produce intense ions providing molecular weight information, are preferable. It is desirable to produce as few ions of different m/z values as possible when using MS-MS following planar separations.

The benefits of FAB/LSIMS and CI are two-fold. First, they usually produce a spectrum with fewer interferences, enabling easier selection of precursor ion. Second, an increase in sensitivity is often achieved if all the ions current obtained from an analyte is concentrated in one ion.

Solar Panel Basics

Solar Panel Basics

Global warming is a huge problem which will significantly affect every country in the world. Many people all over the world are trying to do whatever they can to help combat the effects of global warming. One of the ways that people can fight global warming is to reduce their dependence on non-renewable energy sources like oil and petroleum based products.

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