Thin-layer chromatography (TLC) is a technique which has been applied to a wide range of chemicals since its introduction in the early 1950s. The only limitation to its use is that a suitable method of detection must be available; however, this limitation is removed when the compounds of interest are radiolabelled. Nevertheless, since the introduction of thin-layer radiochromatography (TLRC), one major drawback in gaining widespread acceptance has been the lack of an easy method to quantify the distribution of radioactivity whilst still maintaining good resolution. The available detection methods have either been very time-consuming (e.g. autoradiogra-

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phy) or labour-intensive (e.g. zonal analysis) or could not match the resolution of the TLC separation itself. Over the years TLRC detectors have evolved and significantly improved, starting with scanners in the 1960s, followed by linear analysers in the 1980s and now the new 1990s generation of bioimaging analysers and InstantImager. The limitation of the scanners and linear analysers is that their resolution is lower than can be achieved by TLC itself. New detector technology such as phosphor imaging will lead to a renaissance in the use of TLRC due to the excellent resolution.

Solar Panel Basics

Solar Panel Basics

Global warming is a huge problem which will significantly affect every country in the world. Many people all over the world are trying to do whatever they can to help combat the effects of global warming. One of the ways that people can fight global warming is to reduce their dependence on non-renewable energy sources like oil and petroleum based products.

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