Erythromycin

Erythromycin A (the major and most active component, Figure 2, structure 6), erythromycin B,

OHT I OR

OHT I OR

R

5 CH3

Figure 2 Chemical structures of clarithromycin (5) and erythromycin A (6).

erythromycin C and related compounds in commercial preparations are analysed with an ODS column using a mobile phase consisting of acetonitrile-methanol-0.2 mol L_1 ammonium acetate-water (45 : 10 : 10 : 35, pH adjusted to 7.0-7.8). Erythromycins are detected at 215 nm.

Erythromycin and its metabolites in biological fluids are analysed with an ODS column using a mobile phase consisting of acetonitrile-methanol-0.2 mol L^1 sodium acetate (pH 6.7, 40:5:55). Erythromycin is detected with a dual-electrode electrochemical detector with a detection limit of 10ngmL_1 in plasma. Erythromycin is extracted from plasma with ether, and urine is deproteinized with acetonitrile. Other related erythromycins and degradation products are also resolved.

Solar Panel Basics

Solar Panel Basics

Global warming is a huge problem which will significantly affect every country in the world. Many people all over the world are trying to do whatever they can to help combat the effects of global warming. One of the ways that people can fight global warming is to reduce their dependence on non-renewable energy sources like oil and petroleum based products.

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