Conclusions and Future Prospects

There are no technical barriers preventing the use of affinity separations in the production of biological molecules and entities. The biochemical engineering principles associated with the scale-up and optimization of affinity separations are well developed and the resultant conclusions are readily implemented. The conservatism surrounding their current use stems from the widespread lack of suitable affinity ligands. It is anticipated that novel molecules emerging from new techniques such as phage display technology and combinatorial chemistry will be excellent candidates for use of ligands in affinity separations. Affinity separations will be used in the purification of soluble biomolecules and also in the isolation of more complex species such as viruses, cells and other products for use in gene therapy. Affinity separations will therefore play an essential part in the preparation of future generations of therapeutic biotechnological products. Their adoption will result in the simplication and improvement of downstream processing flow sheets and will enable a rapid transition between discovery and utilization of these products.

K. Brocklehurst, University of London, London, UK Copyright © 2000 Academic Press

Solar Panel Basics

Solar Panel Basics

Global warming is a huge problem which will significantly affect every country in the world. Many people all over the world are trying to do whatever they can to help combat the effects of global warming. One of the ways that people can fight global warming is to reduce their dependence on non-renewable energy sources like oil and petroleum based products.

Get My Free Ebook

Post a comment