Concluding Remarks

The primary advantages of using nonaqueous media for CE may be outlined in four statements:

1. The separation selectivity is improved by using neat organic solvents and the selectivity can easily be altered by changing the nature of the organic solvent or using mixtures of organic solvents.

2. Analysis of hydrophobic compounds is facilitated as their solubility is higher in organic solvents than in aqueous media.

3. Sample preparation is facilitated as extracts obtained with organic solvents may be injected directly into the nonaqueous system (e.g. the eluate from a solid-phase extraction cartridge, when using MeOH or MeCN as the eluent, may be used for CE without further treatment).

4. The relatively low current generated in organic solvents combined with the volatility of the solvents seems to be promising for CE-MS experiments.

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Solar Panel Basics

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