Chiral Surfactants

These can be synthetic optically active amino acid derivatives and natural surfactants, such as glycyrrhic acid, ^-escin, bile salts and digitonin. Digitonin is nonionic, but has been used as a mixed micelle with SDS to give the electrophoretic mobility, to resolve chiral amino acids. These materials are generally water-soluble and can be added easily at micelle concentrations to the electrolytes in MEKC, although viscosity increases should be noted. Initially enan-tiomeric separations were directed towards neutral chiral compounds such as benzoin, and warfarin, a heart drug, which were selectively resolved with materials such as sodium N-dodecanoyl-l-valinate (SDVal) and N-dodecanoyl-l-glutamate (SDGlu). But it was soon realized that charged chiral compounds could also be resolved. Sodium taurocholate (STC) or the taurodeoxycholate (STDC) has been used under acidic conditions for the resolution of dansylated-dl-amino acids and for carboline derivatives and 2,2'-dihydroxy-1,1'-dinaphthyl used under neutral conditions for the drug diltiazem (Figure 5).

Solar Panel Basics

Solar Panel Basics

Global warming is a huge problem which will significantly affect every country in the world. Many people all over the world are trying to do whatever they can to help combat the effects of global warming. One of the ways that people can fight global warming is to reduce their dependence on non-renewable energy sources like oil and petroleum based products.

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