Chiral Separations Table 4 and Figure

The knowledge of the distribution of AA enatiomers in different matrices, and/or the enantiomeric purity of AAs, is of primary importance in the quality control of peptide syntheses for pharmaceuticals/ medicines, as well as in various plant products and in high AA-containing foods, including baby formulas.

For separation and quantitation of enantiomers, HPLC is the method of choice. The application of the three main approaches for enantiomer separation is shown in Table 4 and Figure 7, including direct, chiral mobile-phase additive (CMA) and chiral stationary phase (CSP) and indirect methods (chiral de-rivatization reagent CDR).

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