One surface feature that most proteins have is a binding site that corresponds to their natural physiological role. Enzymes, for example, bind to substrates known as ligands, which may be small molecules or parts of large ones. This binding is often very tight and specific, and can be made use of in separation procedures. The method is called 'affinity chromatography', and exploits the affinity of the protein for its natural ligand. The principle is illustrated in Figure 4. The adsorbent is designed so that it selects out only those proteins that bind to that particular ligand. The proteins may subsequently be eluted using some solute that disrupts the interaction, often just salt or more specifically with the natural ligand, free in solution.

Solar Panel Basics

Solar Panel Basics

Global warming is a huge problem which will significantly affect every country in the world. Many people all over the world are trying to do whatever they can to help combat the effects of global warming. One of the ways that people can fight global warming is to reduce their dependence on non-renewable energy sources like oil and petroleum based products.

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